Department of Clinical Laboratory, Kyoto University Hospital

[1223 / 4E040]

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Ver.19

4.Endocrinological Test >> 4E.Adrenal Medulla Hormones>>4E040 metanephrines, fractionation [urine]

metanephrines, fractionation

[urine]

0

Standard Code (JLAC10)

1	Analyte	4E040	metanephrines, fractionation
	Identification	0000
	Specimen	001	urine (including others)
	Method	205
Result Identifying 01		4E040	55	metanephrine/creatinine ratio
Result Identifying 02		4E040	56	normetanephrine/creatinine ratio
Result Identifying 03		4E040	54	total metanephrine/creatinine ratio
Result Identifying 04		4E040	51	metanephrine
Result Identifying 05		4E040	52	normetanephrine
Result Identifying 06		4E040	53	total metanephrine

Specimen

Top	Colour	Collected Sample	Quantity	Measured Material	Required
White Top		urine	10 mL	urine	2.0 mL

Specimen Rejection Criteria

haemolysis
clotted
lipaemia
inappropriate sample volume
wrong container
urine samples without the appropriate preservative
received ambient
unprotected from light
opening tubes
incterus

Specimen Stability Information

Specimen Type	Container	Temperature	Stability
urine		Refrigerated

Turnaround Time (TAT)

4 - 6 days

Laboratory

outsourcing (SRL, Inc.)weekday (8:30 a.m. - 5:00 p.m.)
night time or weekend

Reference Value

Period / Age

		Male	Female	Unit
Specimen
Method		liquid chromatography-tandem mass spectrometry (LC-MS/MS)
55	metanephrine(creatinine correlated value)	0.04 - 0.22	0.04 - 0.22	μg/mg･Cr
56	normetanephrine(creatinine correlated value)	0.09 - 0.32	0.13 - 0.41	μg/mg･Cr
54	metanephrine+normetanephrine(creatinine correlated value)	***	***	μg/mg･Cr
51	metanephrine(concentration)	***	***	mg/L
52	normetanephrine(concentration)	***	***	mg/L
53	metanephrine+normetanephrine(concentration)	***	***	mg/L

		Male	Female	Unit
Specimen		freshly voided urine
Method		liquid chromatography-tandem mass spectrometry (LC-MS/MS)
51	metanephrine	***	***	mg/L
52	normetanephrine	***	***	mg/L

		Male	Female	Unit
Specimen		freshly voided urine
Method		high performance liquid chromatography (HPLC)
51	metanephrine	***	***	mg/L
52	normetanephrine	***	***	mg/L

		Male	Female	Unit
Specimen
Method

		Male	Female	Unit
Specimen
Method

		Male	Female	Unit
Specimen
Method

		Male	Female	Unit
Specimen
Method

		Male	Female	Unit
Specimen
Method

Critical Value

High Value	Low Value

Kyoto University Hospital

Kyoto University