Department of Clinical Laboratory, Kyoto University Hospital

[3223 / 4E040]

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Ver.18

4.Endocrinological Test >> 4E.Adrenal Medulla Hormones>>4E040 metanephrines, fractionation [pooled urine]

metanephrines, fractionation

[pooled urine]

0

Standard Code (JLAC10)

1	Analyte	4E040	metanephrines, fractionation
	Identification	0000
	Specimen	004	pooled urine
	Method	210	other chromatographies
Result Identifying 01		4E040	51	metanephrine
Result Identifying 02		4E040	52	normetanephrine
Result Identifying 03		4E040	51	metanephrine
Result Identifying 04		4E040	52	normetanephrine
Result Identifying 05		4E040	00

Specimen

Top	Colour	Collected Sample	Quantity	Measured Material	Required
White Top		urine per day (24h)	9 mL		2.0 mL

Specimen Rejection Criteria

haemolysis
clotted
lipaemia
inappropriate sample volume
wrong container
urine samples without the appropriate preservative	reject
received ambient
unprotected from light
opening tubes
incterus

Specimen Stability Information

Specimen Type	Container	Temperature	Stability
pooled urine supernate		Refrigerated	4 weeks

Turnaround Time (TAT)

4 - 5 days

Laboratory

outsourcing (LSI Mediennce Corporation)weekday (8:30 a.m. - 5:00 p.m.)
night time or weekend

Reference Value

Period / Age

		Male	Female	Unit
Specimen		pooled urine
Method		liquid chromatography-tandem mass spectrometry (LC-MS/MS)
51	metanephrine (total value per day)	0.05 - 0.20	0.05 - 0.20	mg/d
52	normetanephrine (total value per day)	0.10 - 0.28	0.10 - 0.28	mg/d
51	metanephrine (concentration)	***	***	mg/L
52	normetanephrine (concentration)	***	***	mg/L
00	metanephrine+normetanephrine (total value per day)	0.15 - 0.41	0.15 - 0.41	mg/d

		Male	Female	Unit
Specimen		pooled urine
Method		liquid chromatography-tandem mass spectrometry (LC-MS/MS)
51	metanephrine (total value per day)	0.04 - 0.18	0.04 - 0.18	mg/d
52	normetanephrine (total value per day)	0.10 - 0.28	0.10 - 0.28	mg/d
51	metanephrine (concentration)	***	***	mg/L
52	normetanephrine (concentration)	***	***	mg/L

		Male	Female	Unit
Specimen		pooled urine
Method		liquid chromatography-tandem mass spectrometry (LC-MS/MS)
51	metanephrine (total value per day)	0.05 - 0.20	0.05 - 0.20	mg/d
52	normetanephrine (total value per day)	0.10 - 0.28	0.10 - 0.28	mg/d
51	metanephrine (concentration)	***	***	mg/L
52	normetanephrine (concentration)	***	***	mg/L

		Male	Female	Unit
Specimen		pooled urine
Method		high performance liquid chromatography (HPLC)
51	metanephrine (total value per day)	0.05 - 0.20	0.05 - 0.20	mg/d
52	normetanephrine (total value per day)	0.10 - 0.28	0.10 - 0.28	mg/d

		Male	Female	Unit
Specimen		pooled urine
Method		high performance liquid chromatography (HPLC)
51	metanephrine (concentration)	***	***	mg/L
52	normetanephrine (concentration)	***	***	mg/L

		Male	Female	Unit
Specimen
Method

		Male	Female	Unit
Specimen
Method

		Male	Female	Unit
Specimen
Method

Critical Value

High Value	Low Value

Kyoto University Hospital

Kyoto University