Department of Diagnostic Pathology, Kyoto University Hospital

[tc13_8d002 / 8D002]

Japanese

Ver.13

8.Other in vitro Test >> 8C.Gene Panel Testing>>8D002 lung cancer related genes (Oncomine Dx Target Test multi CDx system)

lung cancer related genes

(Oncomine Dx Target Test multi CDx system)

0

Standard Code (JLAC10)

1	Analyte	8D002	lung cancer related genes(Oncomine Dx Target Test multi CDx system)
	Identification	9957	comprehensive analysis
	Specimen	070	tissues (including others)
	Method	966	next-generation sequencing
Result Identifying 01		8D002	9957	51
Result Identifying 02		8D002	9957	53
Result Identifying 03		8D002	9957	54
Result Identifying 04		8D002	9957	55
Result Identifying 05		8D002	9957	56
Result Identifying 06		8D002	9957	57
Result Identifying 07		8D002	9957	58
Result Identifying 08		8D002	9957	59
Result Identifying 09		8D002	9957	60
Result Identifying 10		8D002	9957	61
Result Identifying 11		8D002	9957	62
Result Identifying 12		00
Result Identifying 13		00
Result Identifying 14		00
Result Identifying 15		00

Specimen

Top	Colour	Collected Sample	Quantity	Measured Material	Required
		unstained slide	5-10 slides (unstained, 5 micron-thick sections)
		tissue	100mg (5mm*5mm)

Specimen Rejection Criteria

haemolysis
clotted
lipaemia
inappropriate sample volume
wrong container
urine samples without the appropriate preservative
received ambient
unprotected from light
opening tubes
incterus

Specimen Stability Information

Specimen Type	Container	Temperature	Stability
specimen		Ambient

Turnaround Time (TAT)

7 - 11 days

Laboratory

Department of Diagnostic Pathology → outsourcing (LSI Mediennce Corporation)weekday (8:30 a.m. - 5:00 p.m.)
night time or weekend

Reference Value

Period / Age

		Male	Female	Unit
Specimen		tissue
Method		next-generation sequencing
51	BRAF V600E	undetected	undetected
53	ALK Fusion	undetected	undetected
54	ROS1 Fusion	undetected	undetected
55	EGFR Ex19 deletion	undetected	undetected
56	EGFR Ex21 L858R	undetected	undetected
57	EGFR G719X	undetected	undetected
58	EGFR L861Q	undetected	undetected
59	EGFR S768I	undetected	undetected
60	EGFR E709X	undetected	undetected
61	EGFR L861R	undetected	undetected
62	EGFR T790M	undetected	undetected
00	RET Fusion	undetected	undetected
00	ERBB2(HER2)	undetected	undetected
00	MET Ex 14 Skipping	undetected	undetected
00	EGFR Ex20 Insertion	undetected	undetected

		Male	Female	Unit
Specimen		tissue
Method		next-generation sequencing
51	BRAF V600E	undetected	undetected
53	ALK Fusion	undetected	undetected
54	ROS1 Fusion	undetected	undetected
55	EGFR Ex19 deletion	undetected	undetected
56	EGFR Ex21 L858R	undetected	undetected
57	EGFR G719X	undetected	undetected
58	EGFR L861Q	undetected	undetected
59	EGFR S768I	undetected	undetected
60	EGFR E709X	undetected	undetected
61	EGFR L861R	undetected	undetected
62	EGFR T790M	undetected	undetected
00	RET Fusion	undetected	undetected
00	ERBB2(HER2)	undetected	undetected
00	MET Ex 14 Skipping	undetected	undetected

		Male	Female	Unit
Specimen		tissue
Method		next-generation sequencing
51	BRAF V600E	undetected	undetected
53	ALK Fusion	undetected	undetected
54	ROS1 Fusion	undetected	undetected
55	EGFR Ex19 deletion	undetected	undetected
56	EGFR Ex21 L858R	undetected	undetected
57	EGFR G719X	undetected	undetected
58	EGFR L861Q	undetected	undetected
59	EGFR S768I	undetected	undetected
60	EGFR E709X	undetected	undetected
61	EGFR L861R	undetected	undetected
62	EGFR T790M	undetected	undetected
00	RET Fusion	undetected	undetected
00	ERBB2(HER2)	undetected	undetected

		Male	Female	Unit
Specimen		tissue
Method		next-generation sequencing
51	BRAF V600E	undetected	undetected
53	ALK Fusion	undetected	undetected
54	ROS1 Fusion	undetected	undetected
55	EGFR Ex19 deletion	undetected	undetected
56	EGFR Ex21 L858R	undetected	undetected
57	EGFR G719X	undetected	undetected
58	EGFR L861Q	undetected	undetected
59	EGFR S768I	undetected	undetected
60	EGFR E709X	undetected	undetected
61	EGFR L861R	undetected	undetected
62	EGFR T790M	undetected	undetected
00	RET Fusion	undetected	undetected

		Male	Female	Unit
Specimen		tissue
Method		next-generation sequencing
51	BRAF V600E	undetected	undetected
53	ALK Fusion	undetected	undetected
54	ROS1 Fusion	undetected	undetected
55	EGFR Ex19 deletion	undetected	undetected
56	EGFR Ex21 L858R	undetected	undetected
57	EGFR G719X	undetected	undetected
58	EGFR L861Q	undetected	undetected
59	EGFR S768I	undetected	undetected
60	EGFR E709X	undetected	undetected
61	EGFR L861R	undetected	undetected
62	EGFR T790M	undetected	undetected

51 55

		Male	Female	Unit
Specimen		tissue
Method		next-generation sequencing
BRAF V600E	undetected	undetected
EGFR Ex19 deletion	undetected	undetected
56	EGFR Ex21 L858R	undetected	undetected
53	ALK Fusion	undetected	undetected
54	ROS1 Fusion	undetected	undetected

		Male	Female	Unit
Specimen
Method

		Male	Female	Unit
Specimen
Method

Critical Value

High Value	Low Value

Kyoto University Hospital

Kyoto University